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Eleftheria terrae : ウィキペディア英語版
Eleftheria terrae

''Eleftheria terrae'' (abbreviated ''E. terrae'') is a recently discovered Gram-negative bacterium. ''E. terrae'' is a temporary name for the organism, as it was only discovered Fall 2014 and is undergoing scientific study.〔 Teixobactin, a new antibiotic, was found in this bacterium making it an important discovery.〔 The discovery of ''E. terrae'' could represent a new age of antibiotics, as teixobactin is the first new antibiotic discovered since the synthetic era of the 1980s. Prior research has indicated that other uncultivable bacteria like ''E. terrae'' have potential in the development of new antimicrobial agents.〔
==Discovery==
As of 2015, an estimated 99% of bacterial species are uncultured and require advanced means, such as the iChip, to be isolated. ''E. terrae'' is one such bacterium affectionately named by scientists "microbial dark matter" cultivated by emerging scientific methods.〔 A team from Novobiotic Pharmaceuticals led by L. Ling discovered ''Eleftheria terrae'' in the fall of 2014 in a field in Maine using a technique developed at Northeastern University called the iChip or isolation chip technique. The iChip is a small plastic block that contains 192 holes going through it.〔 The holes are filled with a culture medium that are then inoculated with soil diluted to deposit only one bacterium in each hole.〔 After depositing the bacterium in the holes the iChip is covered on both sides by a semipermeable membrane and put into a box of the original soil.〔 The permeable membranes allow nutrients and growth factors from the soil to diffuse in and allow growth of only one species.〔 Ling et al. screened approximately 10,000 iChip growth isolates for prospective antimicrobial activity, and ''E. terrae'' seemed to be hopeful.〔 This technology has potential for discovering even more antibiotics by allowing labs to grow previously “unculturable” microorganisms.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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